Sign in →

Test Code KTHEO THEOPHYLLINE LEVEL

Methodology

Two-point Rate

Theophylline is used in the treatment of bronchial asthma and apnea of the newborn. The measurement of theophylline is useful to assess and adjust dosage for optimal therapeutic level, and for assessing toxicity.

Specimen Requirements

Submit only 1 of the following specimens:

 

Preferred:

Serum

Serum Gel Tube

Container/Tube: Serum gel tube(s)
Specimen Volume: 2 mL (minimum volume: 1 mL) of serum

Collection Instructions: Draw blood 4 hours post an oral dose or any time during continuous intravenous infusion, unless otherwise specified by physician. Spin down within 4 hours of draw.

Note: 1. Date and time of last dose and time of draw are required.

2. Label specimen appropriately (serum).

 

Alternate:

Serum

Plain, Red-Top Tube

Container/Tube: Plain, red-top tube(s)
Specimen Volume: 2 mL (minimum volume: 1 mL) of serum

Collection Instructions: Draw blood 4 hours post an oral dose or any time during continuous intravenous infusion, unless otherwise specified by physician. Spin down within 4 hours of draw.

Note: 1. Date and time of last dose and time of draw are required.

2. Label specimen appropriately (serum).

 

Plasma

Container/Tube: Green-top (lithium heparin) tube(s) or lavender-top (ETDA) tube(s)

Specimen Volume: 2 mL (minimum volume: 1 mL) of plasma

Collection Instructions: Draw blood 4 hours post an oral dose or any time during continuous intravenous infusion, unless otherwise specified by physician. Spin down within 4 hours of draw.

Note: 1. Date and time of last dose and time of draw are required.

2. Label specimen appropriately (plasma).

Day(s) Test Set Up

Monday through Sunday

Reference Values

Therapeutic concentration: 10.0-20.0 µg/mL

Critical concentration (automatic call-back): >25.0 µg/mL

Performing Laboratory

Logan Health Medical Center-Chemistry

Test Classification and CPT Coding

80198

Specimen Transport Temperature

Refrigerate