Test Code KPT PROTHROMBIN TIME INR
Methodology
Fibrin Formation Using Mechanical Clot Detection
Useful for monitoring intensity of oral anticoagulant therapy (Coumadin or warfarin) when combined with international normalized ratio (INR) reporting. It is also useful for screening for hemostatic disorders of the extrinsic pathway (factors II, V, VII, X, and fibrinogen), hepatic disease, or vitamin K deficiency.
Specimen Requirements
Specimen must arrive, be centrifuged, and tested within 24 hours of draw.
Specimen Type: Plasma
Container/Tube: Light-blue top (3.2% buffered sodium citrate, with yellow-striped label)
Specimen Volume: Full tube
Collection Instructions:
1. Tube must be filled to capacity.
2. Ratio of blood to anticoagulant is critical for valid coagulation results (9:1).
3. Send whole blood in original tube.
Additional Information: Hemolyzed specimen is not acceptable.
Day(s) Test Set Up
Monday through Sunday
Reference Values
PT
12.0 -14.9 seconds
INR
2.0-3.5
Critical value (automatic call-back):
≤ 18 Years Protime > 30.0 seconds
INR > 4.0
> 18 Years INR ≥ 5.0
Note: The INR was developed to standardize reporting of the PT assay test results for patients on oral anticoagulant therapy. This was necessary because variability in responsiveness of the different instrument and thromboplastin reagent combinations available resulted in dosing differences.
Performing Laboratory
Logan Health Medical Center Laboratory
Test Classification and CPT Coding
85610
Specimen Transport Temperature
Ambient 24 hours-Whole blood