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Test Code CDOMB Cadmium for Occupational Monitoring, Blood

Reporting Name

Cadmium Occupational Monitor, B

Useful For

Detecting exposure to cadmium, a toxic heavy metal

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Whole blood


Specimen Required


Patient Preparation: High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Container/Tube: Royal blue top (EDTA) Vacutainer plastic trace element blood collection tube

Specimen Volume: Full tube

Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole blood Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

0.0-4.9 mcg/L

Reference values apply to all ages.

Day(s) Performed

Monday through Saturday

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82300

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CDOMB Cadmium Occupational Monitor, B 5609-3

 

Result ID Test Result Name Result LOINC Value
89539 Cadmium Occupational Monitor, B 5609-3

Clinical Information

The toxicity of cadmium resembles the other heavy metals (arsenic, mercury, and lead) in that it attacks the kidney; renal dysfunction with proteinuria with slow onset (over a period of years) is the typical presentation. Breathing the fumes of cadmium vapors leads to nasal epithelial deterioration and pulmonary congestion resembling chronic emphysema.

 

The most common source of chronic exposure comes from spray painting of organic-based paints without use of a protective breathing apparatus; auto repair mechanics represent a susceptible group for cadmium toxicity. Tobacco smoke is another common source of cadmium exposure.

Interpretation

Normal blood cadmium is <5.0 mcg/L, with most results in the range of 0.5 to 2.0 mcg/L.

 

Acute toxicity will be observed when the blood level exceeds 50 mcg/L.

Cautions

High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen cannot be collected for 96 hours.

Report Available

1 to 2 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)