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Test Code ACET.1 ACETAMINOPHEN LEVEL

Methodology

Colorimetric

Useful for suspected overdose or to measure therapeutic levels when used as an antipyretic or analgesic.

Specimen Requirements

Submit only 1 of the following specimens:

 

Preferred:

Serum

Serum Gel Tube

Container/Tube: Serum gel tube(s)
Specimen Volume: 1 mL (minimum volume: 0.5 mL) of serum

Collection Instructions: If an overdose is suspected, draw specimen 4 to 12 hours post-ingestion. For therapeutic drug monitoring a peak level is drawn 1 hour after completion of dose. Spin down within 4 hours of draw.

Note: 1. Date and time of last dose and time of draw are required.

2. Label specimen appropriately (serum).

 

Alternate:

Serum

Plain, Red-Top Tube

Container/Tube: Plain, red-top tube(s)
Specimen Volume: 1 mL (minimum volume: 0.5 mL) of serum

Collection Instructions: If an overdose is suspected, draw specimen 4 to 12 hours post-ingestion. For therapeutic drug monitoring a peak level is drawn 1 hour after completion of dose. Spin down within 4 hours of draw.

Note: 1. Date and time of last dose and time of draw are required.

2. Label specimen appropriately (serum).

 

Plasma

Container/Tube: Green-top (lithium heparin) tube(s) or lavender-top (ETDA) tube(s)

Specimen Volume: 1 mL (minimum volume: 0.5 mL) of plasma

Collection Instructions: If an overdose is suspected, draw specimen 4 to 12 hours post-ingestion. For therapeutic drug monitoring a peak level is drawn 1 hour after completion of dose. Spin down within 4 hours of draw.

Note: 1. Date and time of last dose and time of draw are required.

2. Label specimen appropriately (plasma).

Day(s) Test Set Up

Monday through Sunday

Reference Values

Therapeutic concentration: 10-30 µg/mL

Toxic concentrations

4 hours post dose: >150 µg/mL

12 hours post dose: >50 µg/mL

Critical concentration (automatic call-back): >60 µg/mL

Performing Laboratory

Logan Health Medical Center-Chemistry

Test Classification and CPT Coding

80375

Specimen Transport Temperature

Refrigerate