Test Code ACET.1 ACETAMINOPHEN LEVEL
Methodology
Colorimetric
Useful for suspected overdose or to measure therapeutic levels when used as an antipyretic or analgesic.
Specimen Requirements
Submit only 1 of the following specimens:
Preferred:
Serum
Serum Gel Tube
Container/Tube: Serum gel tube(s)
Specimen Volume: 1 mL (minimum
volume: 0.5 mL) of serum
Collection Instructions: If an overdose is suspected, draw specimen 4 to 12 hours post-ingestion. For therapeutic drug monitoring a peak level is drawn 1 hour after completion of dose. Spin down within 4 hours of draw.
Note: 1. Date and time of last dose and time of draw are required.
2. Label specimen appropriately (serum).
Alternate:
Serum
Plain, Red-Top Tube
Container/Tube: Plain, red-top tube(s)
Specimen Volume: 1 mL (minimum
volume: 0.5 mL) of serum
Collection Instructions: If an overdose is suspected, draw specimen 4 to 12 hours post-ingestion. For therapeutic drug monitoring a peak level is drawn 1 hour after completion of dose. Spin down within 4 hours of draw.
Note: 1. Date and time of last dose and time of draw are required.
2. Label specimen appropriately (serum).
Plasma
Container/Tube: Green-top (lithium heparin) tube(s) or lavender-top (ETDA) tube(s)
Specimen Volume: 1 mL (minimum volume: 0.5 mL) of plasma
Collection Instructions: If an overdose is suspected, draw specimen 4 to 12 hours post-ingestion. For therapeutic drug monitoring a peak level is drawn 1 hour after completion of dose. Spin down within 4 hours of draw.
Note: 1. Date and time of last dose and time of draw are required.
2. Label specimen appropriately (plasma).
Day(s) Test Set Up
Monday through Sunday
Reference Values
Therapeutic concentration: 10-30 µg/mL
Toxic concentrations
4 hours post dose: >150 µg/mL
12 hours post dose: >50 µg/mL
Critical concentration (automatic call-back): >60 µg/mL
Performing Laboratory
Logan Health Medical Center-Chemistry
Test Classification and CPT Coding
80375
Specimen Transport Temperature
Refrigerate