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Test Code 2C19 Cytochrome P450 2C19 (PLAVIX®) Genotype, Blood

Methodology

The eSensor® 2C19 Test uses a solid-phase electrochemical method for determining the CYP2C19 mutation status of a defined panel of CYP2C19 mutations.

This test confirms the presence of genotypes that affect the metabolism of drugs, such as PLAVIX®, that are metabolized by cytochrome CYP2C19.

Specimen Requirements

Container/Tube: Lavender-top (EDTA) tube(s)

Specimen Volume: 3 mL (minimum volume: 1 mL) of whole blood

Collection Instructions: Do not centrifuge.

Day(s) Test Set Up

Monday through Friday

Reference Values

2C19 *1/*1

Performing Laboratory

Logan Health Medical Center Laboratory

Test Classification and CPT Coding

Test Classification:

This test was developed and its performance characteristics determined by Logan Health Medical Center, Kalispell, MT. It has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code:

83891-Extraction

83892-Enzymatic digestion
83900-Amplification, target, multiplex, first 2 nucleic acid sequences
83901 x 9-Amplification, target, multiplex, each additional nucleic acid sequence beyond 2
88384-Array-based evaluation, 11 to 50 probes

Specimen Transport Temperature

Ambient/Refrigerate OK